In the case of TCA (tricyclic antidepressant) overdose, which of the following ECG changes may be present?

In the case of TCA (tricyclic antidepressant) overdose, which of the following ECG changes may be present?

• A. Shortened QT interval
• B. Broad complex VT
• C. Sinus tachycardia
• D. Atrial fibrillation

Answer: (B)

In the context of tricyclic antidepressant (TCA) overdose, broad complex ventricular tachycardia (VT) is a significant and characteristic electrocardiogram (ECG) abnormality that may occur. TCAs are known to block sodium channels, which can lead to a slowing of conduction in the heart and subsequently manifest as a widened QRS complex on the ECG. When the QRS complex is widened significantly (greater than 100 milliseconds), it can lead to the development of broad complex VT, which is an immediate concern in the setting of cardiac toxicity from TCA overdose. Recognizing broad complex VT is critical because it can indicate severe cardiac compromise and signifies the need for rapid intervention. TCA overdoses can lead to arrhythmias due to their effects on cardiac conduction, and broad complex VT can be life-threatening, thus requiring immediate resuscitative measures. Awareness of this ECG change in the context of TCA overdose is essential for effective patient management.

In the context of tricyclic antidepressant (TCA) overdose, broad complex ventricular tachycardia (VT) is a significant and characteristic electrocardiogram (ECG) abnormality that may occur. TCAs are known to block sodium channels, which can lead to a slowing of conduction in the heart and subsequently manifest as a widened QRS complex on the ECG. When the QRS complex is widened significantly (greater than 100 milliseconds), it can lead to the development of broad complex VT, which is an immediate concern in the setting of cardiac toxicity from TCA overdose.

Recognizing broad complex VT is critical because it can indicate severe cardiac compromise and signifies the need for rapid intervention. TCA overdoses can lead to arrhythmias due to their effects on cardiac conduction, and broad complex VT can be life-threatening, thus requiring immediate resuscitative measures. Awareness of this ECG change in the context of TCA overdose is essential for effective patient management.